Quantitative analysis of andrographolide, a biomarker of Andrographis paniculata, using qNMR spectroscopy
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چکیده
منابع مشابه
Is Andrographis paniculata extract and andrographolide anaphylactic?
Andrographis paniculata, "King of bitters" is a popularly known medicinal plant extensively used in many parts of the world for treatment of various diseases. Since recent past, anaphylactic/allergic type adverse events were reported upon A. paniculata usage, the study aimed to evaluate the anaphylactic and anaphylactoid potential of A. paniculata extract and andrographolide (a major phytoactiv...
متن کاملAndrographolide isolated from Andrographis paniculata Ness
Andrographolide isolated from Andrographis paniculata Ness (A and 1.40 mM induced DNA fragmentation and increased the percentage o breast cancer cell line was treated for 24 , 48 and 72 h. The results de induce apoptosis in TD-47 human breast cancer cell line in a time and increase expression of p53, bax , caspase-3 and decrease ex immunohistochemical analysis.
متن کاملStability of Andrographolide in Andrographis Paniculata under Selected Storage Conditions
Fresh Andrographis paniculata was dried by a thin layer drying technique using hot air at a temperature of 55°C and velocity of 1.0 m/s. The dried sample was then ground and kept in air-tight glass bottles at three selected storage conditions (5±2°C; 25±2°C with 60% ± 5% RH; 30±2°C with (60% ± 5%RH) for three months period. The contents of the active compound andrographolide present in the drie...
متن کاملAntifungal activity of the extract of Andrographis paniculata and andrographolide
Antifungal activity assay of the methanol extract of the aerial parts of the plant Andrographis paniculata revealed that it exhibits mycelial growth inhibition of Fusarium solani and spore germination inhibition of Alternaria solani. Pure andrographolide present in the methanol extract also exhibited spore germination inhibition of A. solani. Quantitative estimation of andrographolide in the me...
متن کاملAP-1/IRF-3 Targeted Anti-Inflammatory Activity of Andrographolide Isolated from Andrographis paniculata
Andrographolide (AG) is an abundant component of plants of the genus Andrographis and has a number of beneficial properties including neuroprotective, anticancer, anti-inflammatory, and antidiabetic effects. Despite numerous pharmacological studies, the precise mechanism of AG is still ambiguous. Thus, in the present study, we investigated the molecular mechanisms of AG and its target proteins ...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2019
ISSN: 1663-9812
DOI: 10.3389/conf.fphar.2019.63.00005